Dr. Roger J. Packer The Childhood Brain Tumor Foundation was pleased to be a Silver Sponsor for the comprehensive 17th International Symposium on Pediatric Neuro-Oncology. Our Neurotransmitter Fall-Winter edition will cover other topics from the other conference. This summary covers a topic from Family Day and Educational Day, held June 11, 2016, related to molecular …
Carl D. Novina, M.D., Ph.D.Dana-Farber Cancer Institute NEW-first of two-years 2019-2020 “The central organizing idea of biology (dogma) is that DNA (the blueprint of a cell), makes RNA (a messenger of information contained in the DNA) which in turn makes proteins (which carry out the activities of a cell). Whereas most scientists and physicians study …
Stephen C. Mack, Ph.D., Baylor College of Medicine, Texas Children’s one-year study, final summary We are grateful for support provided by the CBTF and funders that have allowed us to pursue our project on the characterizing “The Role of MOS Proto-Oncogene in H3.3K27M Diffuse Intrinsic Pontine Glioma”. Diffuse intrinsic pontine glioma (DIPG) remains a fatal …
PI: J. Bryan Iorgulescu, Weill Cornell Medical College, 2011-2012 I have a deep-seated passion for pediatric neuro-oncology research and wish to pursue a career where I can directly fight children’s brain cancers – & hopefully one day, help find a cure. Delving into this project along side my medical school studies at Weill Cornell Medical …
Charles Eberhart, M.D., Ph.D. 2010-2011 funding Diffuse intrinsic pontine gliomas (DIPG) are among the most deadly pediatric brain cancers, with no effective therapies. Unfortunately, few models for these exist, severely limiting our ability to test new treatments for the patients who need them most. The goal of our research proposal is to develop accurate models …
Kathy Warren, M.D., NCI Special Project funded 2010-2011 Children with diffuse intrinsic pontine gliomas (DIPG) continue to have a poor outcome despite advances in radiation oncology, new chemotherapeutic agents and extensive research into overcoming drug resistance. One of the major obstacles is the lack of biological studies that may aid us in better understanding the …
Background Primary CNS tumors are the most common pediatric solid cancer, and account for 23% of malignancy in children under 15 years of age, second only to leukemia. The incidence of newly diagnosed brain tumors in the pediatric population is 3.3 cases per 100,000 children, with 3,000 children diagnosed annually. Brain tumors are also the …
Javad Nazarian, Ph.D., Assistant Professor, Pediatrics, Children’s National Medical Center, Center for Genetic Medicine The focus of my science career changed almost three years ago when a physician colleague approached me and proposed a potentially challenging project: molecular analysis of pediatric brainstem gliomas (BSGs). The project deemed challenging because of the lack of fresh frozen …
