Sameer Keole, M.D. Medical Director, ProCure Proton Therapy Center in Oklahoma City When a child is diagnosed with cancer it is devastating for the entire family. The good news is that cure rates for childhood cancer are at nearly 80 percent thanks to ongoing research that has improved the diagnosis and treatment of pediatric cancers. …
Brendan Price, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA. Pediatric high-grade gliomas (pHGG) have few treatment options and most children diagnosed only survive for 1-2 years. Identifying new treatments is therefore of the highest priority. Work in the lab is focused on understanding how these brain tumors arise, with the …
Jian Teng, Ph.D., Massachusetts General Hospital one-year 2018-2019 final summary I want to take this opportunity to sincerely thank CBTF for your funding to my proposal of using a subset of quinoline methanol anti-malaria agents in killing pediatric brain cancer cells. This funding helps us get one step closer to our goal. With the funding …
Kevin Bielamowicz Poor outcomes for children with high grade glioma (HGG) warrant novel therapeutic strategies, and redirecting immune cells can achieve this aim while minimizing side effects to normal cells. Using mathematical modeling in a group of brain tumor samples, we discovered substantial variation between individual cells within the same tumor as well as between …
Kevin Bielamowicz, M.D., Arkansas Research Institute 2016, second year Poor outcomes for children with high grade glioma (HGG) warrant novel therapeutic strategies, and redirecting immune cells can achieve this aim while minimizing side effects to normal cells. Using mathematical modeling in a group of brain tumor samples, we discovered substantial variation between individual cells within …
Eva Perdahl, MD, PhD, Children’s National-VA and David Wolf, MD, PhD, Johns Hopkins University Brain tumors are the most common solid tumor of childhood. Among brain tumors, low-grade gliomas are the most common type, accounting for almost 50% of all tumor types. There are two major types of cells that make up the brain: neurons …
Paul Graham Fisher, M.D., M.H.S. and Michelle Monje, M.D., Ph.D Brain stem tumors are perhaps the most dreaded cancers in pediatric oncology, owing to their historically poor prognosis, yet they remain an area of intense research. Brain stem tumors account for about 10 to 15% of childhood brain tumors. Peak incidence for these tumors occurs …
PI: J. Bryan Iorgulescu, Weill Cornell Medical College, 2011-2012 I have a deep-seated passion for pediatric neuro-oncology research and wish to pursue a career where I can directly fight children’s brain cancers – & hopefully one day, help find a cure. Delving into this project along side my medical school studies at Weill Cornell Medical …
Javad Nazarian, Ph.D., Assistant Professor, Pediatrics, Children’s National Medical Center, Center for Genetic Medicine The focus of my science career changed almost three years ago when a physician colleague approached me and proposed a potentially challenging project: molecular analysis of pediatric brainstem gliomas (BSGs). The project deemed challenging because of the lack of fresh frozen …
