As the care of children with brain tumors evolves, there is recognition that despite advances in surgery, chemotherapy and radiation therapy, there are clear needs to explore other options and to create mechanisms where new therapeutic approaches can be assessed carefully and expeditiously. Over the past 2 decades, multiple clinical trials consortia have been developed …
Dr. Roger J. Packer The Childhood Brain Tumor Foundation was pleased to be a Silver Sponsor for the comprehensive 17th International Symposium on Pediatric Neuro-Oncology. Our Neurotransmitter Fall-Winter edition will cover other topics from the other conference. This summary covers a topic from Family Day and Educational Day, held June 11, 2016, related to molecular …
Brain tumors are the second most common type of malignancy in children less than 2 years of age. Furthermore, brain tumors as a whole are the most common solid tumor of childhood and 12-15% of all childhood brain tumors occur in children less than two. Childhood brain tumors occur in males more frequently than in …
John Y.H. Kim, MD, Baylor College of Medicine, Houston, TX Pediatrics became the focus of my clinical interests because of its intrinsic orientation toward developmental issues. I have since had the great fortune of serving children and their families who have charged me with my life’s work. No group of patients and families appeared to …
Sameer Keole, M.D. Medical Director, ProCure Proton Therapy Center in Oklahoma City When a child is diagnosed with cancer it is devastating for the entire family. The good news is that cure rates for childhood cancer are at nearly 80 percent thanks to ongoing research that has improved the diagnosis and treatment of pediatric cancers. …
Yin Wang, Ph.D. First-year Children’s National, DC; University of Maryland, Baltimore Two-year study, second year Dr. Wang’s group has made significant progress for their project, “A Novel Mechanism and Immediately-Translatable Targeted-Therapy for Group 3 Medulloblastoma”. Their completed studies have demonstrated that HIF1α is a driver for infant Group 3 medulloblastoma (G3MB) by reciprocal positive regulation …
Huadong Pei, Ph.D., The George Washington University New Funding Summary, first of two years Medulloblastoma is the most common and aggressive type of brain tumor in children. It originates in the back part of the brain called the cerebellum. In up to 1/3 of cases, it can spread to other parts of the brain and …
Allison Martin, M.D. Medulloblastoma is the most common malignant brain tumor in children. In cases of relapsed or refractory disease there is no known curative therapy. To address this question we have generated fetal mouse brain cells that mimic the most aggressive phenotype of medulloblastoma called “anaplastic” when they are placed into the cerebellum of …
Medulloblastoma is the most common primary malignant central nervous system tumor arising in childhood. Survival rates for children with medulloblastomas have nearly doubled and so has the recognition that many survivors are impaired and new forms of treatment are needed. Its understanding and management represents both the progress and challenges involved in the treatment of …
