The Hedgehog Pathway in Diffuse Intrinsic Pontine Glioma
Philip Beachy, Ph.D. and Michelle Monje, M.D. 2010-2011 funding Diffuse intrinsic pontine glioma (DIPG) is a devastating childhood brain tumor that is poorly understood and universally fatal. Progress to date has been limited by a lack of faithful experimental model systems. We have overcome this impasse by generating new DIPG cell lines and xenograft model …