Normal brain is made up of several cell types including neurons, the main functional cell of the brain, and glia, which play a supportive role to the neurons. Glia are further subdivided into different types, each type with a different function, including oligodendrocytes which cover the axons of neurons with sheathes of myelin, and astrocytes …
LINK TO ARTICLE: Stanford Medicine/Monje Labs/Neurology and Neurological Sciences
Brain tumors are the second most common type of malignancy in children less than 2 years of age. Furthermore, brain tumors as a whole are the most common solid tumor of childhood and 12-15% of all childhood brain tumors occur in children less than two. Childhood brain tumors occur in males more frequently than in …
Jonathan L. Finlay, MB ChB, FRCP (Lond.), FRCPCH, Director, Neuro-oncology Program; Elizabeth and Richard Germain Endowed Professor of Pediatric Cancer, Division of Peduiatric Hematology, Oncology and Blood & Marrow Transplant, Nationwide Children’s Hospital. Professor of Pediatrics and Radiation Oncology, The Ohio State University, Columbus, Ohio, USA The family of tumors known as germ cell tumors …
Kathy Warren, MD, pediatric oncologist, National Cancer Institute INTRODUCTION: Although ependymomas are the third most common type of brain tumor in children (following astrocytoma and medulloblastoma), they are relatively rare, with approximately 200 cases diagnosed in the US each year in children and adults less than 25 years of age. Ependymomas account for 6-12% of …
Eva Perdahl, MD, PhD, Children’s National-VA and David Wolf, MD, PhD, Johns Hopkins University Brain tumors are the most common solid tumor of childhood. Among brain tumors, low-grade gliomas are the most common type, accounting for almost 50% of all tumor types. There are two major types of cells that make up the brain: neurons …
Paul Graham Fisher, M.D., M.H.S. and Michelle Monje, M.D., Ph.D Brain stem tumors are perhaps the most dreaded cancers in pediatric oncology, owing to their historically poor prognosis, yet they remain an area of intense research. Brain stem tumors account for about 10 to 15% of childhood brain tumors. Peak incidence for these tumors occurs …
Background Primary CNS tumors are the most common pediatric solid cancer, and account for 23% of malignancy in children under 15 years of age, second only to leukemia. The incidence of newly diagnosed brain tumors in the pediatric population is 3.3 cases per 100,000 children, with 3,000 children diagnosed annually. Brain tumors are also the …
Medulloblastoma is the most common primary malignant central nervous system tumor arising in childhood. Survival rates for children with medulloblastomas have nearly doubled and so has the recognition that many survivors are impaired and new forms of treatment are needed. Its understanding and management represents both the progress and challenges involved in the treatment of …
