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Late Effects

Neurotoxicity

12/27/2019 by Jeanne Young

Changes in the Brains of Children with Brain Tumors of the Central Nervous System Neurotoxicity is a significant tumor-and treatment-related complication for a number of childhood cancer survivors. It is particularly relevant for children with brain tumors who require therapy specifically directed at the central nervous system. Despite its significance, relatively little is known about …

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Cerebellar Mutism

11/01/2019 by Jeanne Young

by Loice Swisher, M.D., co-authored by Dr. Peter Philips New resources added at the end of this article. A child s loss of speech after removal of a cerebellar tumor was initially described in 1958 (Daly and Love 1958). Cerebellar mutism was first reported in 1979 by Hirsch after a posterior fossa tumor resection.  In …

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The Visual System and Childhood Brain Tumor

10/22/2019 by Jeanne Young

Michael X. Repka, M.D., Vice Chair for Clinical Practice, Wilmer Eye Institute, Professor of Ophthalmology, Johns Hopkins University School of Medicine, N. Wolfe Street, Baltimore, MD 21287-9028  Childhood brain tumors present with visual symptoms about 50% of the time.  Additionally, children will develop visual symptoms and/or signs during and after treatment.  Such signs may become …

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Survivors of Childhood Brain Tumors: the Potential for Late Effects

04/01/2013 by Jeanne Young

Sara Bottomley, RN, MSN, CPNP The survival rate of patients with childhood brain tumors continues to improve.  However, survivors are at risk for a variety of physical, medical, cognitive, and/or psychosocial late effects.  These late effects may be directly related to the type, location and extent of the brain tumor itself or a result of …

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Hypopituitarism in Pediatric Brain Tumor Survivors

12/01/2012 by Jeanne Young

Dr. Maya Lodish, pediatric endocrinologist National Institute of Child Health and Human Development National Institutes of Health, Bethesda, MD Survivors of childhood brain tumors are at an especially high risk for damage to the endocrine system. The endocrine system is comprised of glands and hormones that help to control specific functions of the body, such …

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Behavior Problems in Children who have Undergone Treatment for Brain Tumors

08/01/2012 by Jeanne Young

Mary Ann McCabe, Ph.D., clinical psychologist, Society for Research in Child Development Children and adolescents who have undergone treatment for brain tumors may be more likely to exhibit behavior problems than their peers. There have been relatively few formal studies of this issue, and behavior problems have often not been included in studies of neuropsychological …

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