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Treatments and Therapy

Advances in Surgical Technique for Childhood Brain Tumors

11/22/2019 by Jeanne Young

Introduction I will divide advances in surgical technique over the past several decades into 4 major categories: greater visual magnification, improved aids to navigation, better functional brain mapping, and more precise tumor destruction. Magnification The operating neurosurgical microscope has been used since the 1950’s when Dr. RMP Donaghy of the University of Vermont was active …

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Targeted Radio-Immunotheraphy for Malignant Brainstem Glioma

11/01/2011 by Jeanne Young

PI:  J. Bryan Iorgulescu, Weill Cornell Medical College, 2011-2012 I have a deep-seated passion for pediatric neuro-oncology research and wish to pursue a career where I can directly fight children’s brain cancers – & hopefully one day, help find a cure. Delving into this project along side my medical school studies at Weill Cornell Medical …

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Molecular Profiling of Pediatric Cancer

12/27/2010 by Jeanne Young

Eric Raabe MD, PhD One of the goals of pediatric cancer treatment is deploying personalized medicine. Treating each patient and each tumor, with exactly the right type of therapy to maximize killing of tumor cells and minimize side effects to patients is the objective. Initially, brain tumors were classified by their appearance under the microscope. …

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Radiosurgery Expands Treatment Options for Children and Infants with Tumors of the Brain and Spine

04/01/2010 by Jeanne Young

Nothing is more frightening than to learn that your child has a brain tumor. These serious tumors are unfortunately all too common; in fact, malignant brain tumors are the most frequent type of solid cancer seen in childhood. To make matters more difficult, conventional radiation therapy – a mainstay of treatment for adults – cannot …

Read moreRadiosurgery Expands Treatment Options for Children and Infants with Tumors of the Brain and Spine

Cancer Stem Cells: A New Paradigm

12/01/2008 by Jeanne Young

by David M. Panchision, Ph.D., Investigator, Center for Neuroscience Research, Children’s National Medical Center, Washington, DC Central Nervous System (CNS) tumors are one of the most prevalent forms of cancer in the U.S. and are the leading cause of cancer deaths in children (1-3). Current therapies can affect all cells, as with radiation, or highly …

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Stereotactic Radiosurgery

12/01/1998 by Jeanne Young

Michael R. Kuettel, M.D., Ph.D. Abstract: Stereotactic radiation is a method of delivering focused irradiation to both benign and cancerous lesions. This form of treatment can be administered in single or multiple fractions (radiosurgery or stereotactic radiotherapy, respectively). This technology has evolved rapidly due to advances in both hardware and software design. Clinical indications for …

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