Normal brain is made up of several cell types including neurons, the main functional cell of the brain, and glia, which play a supportive role to the neurons. Glia are further subdivided into different types, each type with a different function, including oligodendrocytes which cover the axons of neurons with sheathes of myelin, and astrocytes …
LINK TO ARTICLE: Stanford Medicine/Monje Labs/Neurology and Neurological Sciences
Brain tumors are the second most common type of malignancy in children less than 2 years of age. Furthermore, brain tumors as a whole are the most common solid tumor of childhood and 12-15% of all childhood brain tumors occur in children less than two. Childhood brain tumors occur in males more frequently than in …
Jonathan L. Finlay, MB ChB, FRCP (Lond.), FRCPCH, Director, Neuro-oncology Program; Elizabeth and Richard Germain Endowed Professor of Pediatric Cancer, Division of Peduiatric Hematology, Oncology and Blood & Marrow Transplant, Nationwide Children’s Hospital. Professor of Pediatrics and Radiation Oncology, The Ohio State University, Columbus, Ohio, USA The family of tumors known as germ cell tumors …
Kathy Warren, MD, pediatric oncologist, National Cancer Institute INTRODUCTION: Although ependymomas are the third most common type of brain tumor in children (following astrocytoma and medulloblastoma), they are relatively rare, with approximately 200 cases diagnosed in the US each year in children and adults less than 25 years of age. Ependymomas account for 6-12% of …
by Loice Swisher, M.D., co-authored by Dr. Peter Philips New resources added at the end of this article. A child s loss of speech after removal of a cerebellar tumor was initially described in 1958 (Daly and Love 1958). Cerebellar mutism was first reported in 1979 by Hirsch after a posterior fossa tumor resection. In …
Eva Perdahl, MD, PhD, Children’s National-VA and David Wolf, MD, PhD, Johns Hopkins University Brain tumors are the most common solid tumor of childhood. Among brain tumors, low-grade gliomas are the most common type, accounting for almost 50% of all tumor types. There are two major types of cells that make up the brain: neurons …
Eric Raabe MD, PhD One of the goals of pediatric cancer treatment is deploying personalized medicine. Treating each patient and each tumor, with exactly the right type of therapy to maximize killing of tumor cells and minimize side effects to patients is the objective. Initially, brain tumors were classified by their appearance under the microscope. …
Medulloblastoma is the most common primary malignant central nervous system tumor arising in childhood. Survival rates for children with medulloblastomas have nearly doubled and so has the recognition that many survivors are impaired and new forms of treatment are needed. Its understanding and management represents both the progress and challenges involved in the treatment of …
